Dermal Fillers for Lost Collagen

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Dermal Fillers for Lost Collagen

Restylane®, Juvederm®, and More Are Ideal for Lip Injections, Smoothing Wrinkles, and Other Treatments in Denver

One of the primary reasons women and men alike begin to show signs of aging is loss of the skin’s structural support (especially collagen). Denver’s AboutSkin Dermatology team regularly provides consultations with patients who want to address any of a number of facial changes, including volume loss and the development of nasolabial folds and similar creases, thin lips, and facial hollows. All of these cosmetic issues can be attributed to collagen loss and changes in the structural support of the skin. Fortunately, they can also all be minimized and addressed with dermal fillers.


Fillers can restore volume in areas of the face, hands, and chest. Dr. Joel Cohen of AboutSkin Dermatology has participated in numerous clinical trials on dermal fillers—including Restylane®, Restylane Lyft® (face and hands), Radiesse® (cheek and jawline), Voluma® (cheek), Juvederm® (lip, nasolabial folds, and marionette area), etc. AboutSkin Dermatology’s team of Board-Certified Dermatologists has the experience and expertise to treat your volume loss and rejuvenate your skin.

Dr. Joel Cohen is an international instructor, teaching physicians all over the world techniques and applications for dermal fillers. His lessons, lectures, and speaking engagements are based on his years of experience, since he has participated in the clinical trials and injection protocols of MANY facial injectables used for facial folds, lip volume, lip lines, cheek augmentation, jawline contouring, and more. The AboutSkin team is made up of Board-Certified Dermatologists who all work with injectables daily—giving them the focus and knowledge necessary for helping patients to reach their cosmetic dermatology goals.

What Does Collagen Do?

Collagen is a structural protein found throughout the human body. Its main role is to provide flexible structure and support—especially for the skin.

In the skin, collagen not only works as an internal scaffold that keeps tissues elevated in youthful positions, but it also creates space for “storing” other structural components of the skin, such as hyaluronic acid (HA). HA sugar molecules can hold up to 1,000 times their own weight in water, making them critically important for hydration and supporting the skin.

Collagen molecules are not permanent. They actually break down due to both the passage of time and the effects of environmental exposure, such as sunlight.

The body tries to constantly replenish collagen molecules to maintain their presence in the skin, but this natural process begins to slow and taper off as a person ages. Eventually, the creation of new collagen can no longer keep pace with the destruction of old collagen. This causes collagen levels to drop, which leads to a loss of structure, flexibility, and moisture. Dermal fillers can help minimize the appearance of significant collagen loss.

How Do Dermal Fillers Work?

While many dermal fillers in the past contained actual collagen, the most commonly used options today have hyaluronic acid as their base. Facial injectables typically take the form of a clear gel, which adds volume in areas where collagen loss has caused hollowing, drooping, or folds.

By filling in these areas of collagen deficiency, the skin regains more youthful contours, prominences, roundness, and smoothness. While the effect of fillers is temporary, with the body gradually absorbing the hyaluronic acid, many fillers last for months or even a few years (often depending on the movement in the area of placement, as well as the agent actually injected).

Discover what injectors can do with dermal fillers at the Denver area's AboutSkin Dermatology.
The AboutSkin Dermatology team can accomplish a wide range of rejuvenating effects with dermal fillers. Denver-area women and men can alter their facial contours, proportions, and shape by adding volume to their forehead, cheeks, lips, chin, and jawline. Fillers can also address hollows under the eyes and at the temples, smooth creases and lines between the eyebrows and around the mouth, and reduce the appearance of veins and tendons so the backs of the hands appear younger.

What Dermal Fillers Are Available?

AboutSkin Dermatology carries numerous dermal fillers to be able to meet the unique cosmetic need of a diverse range of patients. Some fillers are better suited to specific areas, with benefits that make them ideal in certain cases. Options include:


Learn more about the two types of Restylane® filler at the Denver area's AboutSkin
See how the Non-Animal Stabilized Hyaluronic Acid (NASHA) and Optimal Balance Technology (OBT) gels compare when it comes to Restylane® at the Denver area’s AboutSkin Dermatology.

This HA-based filler can be used to address moderate to severe nasolabial folds and volume loss, as well as for lip enhancement. AboutSkin participated in an FDA trial on Restylane®.

Restylane Lyft®

This HA filler adds fullness to the cheeks to address volume loss that causes contour changes. It can also be used on the hands. AboutSkin participated in the FDA trials on Restylane Lyft® (face and hands).

Restylane Silk®

Primarily used for etched lines and lip augmentation, this HA filler is great for imprinted lines (especially wrinkles around the mouth in patients who don’t yet want laser resurfacing).

Learn About Restylane’s Technology – Watch

*Individual results may vary

Restylane Refyne®

The hyaluronic acid in this filler helps to soften nasolabial folds and marionette lines while maintaining flexibility and enhancing support of the muscular structures below the skin.

Restylane Defyne®

Similar to Refyne®, this option is formulated to smooth and reflate deeper, more severe nasolabial folds and marionette lines.

Juvederm® Ultra and Ultra Plus

Hyaluronic acid-based fillers in this family are ideal for plumping up thin lips and reducing the appearance of nasolabial folds. AboutSkin participated in clinical trials on Juvederm® for the lips, nasolabial folds, and marionette areas.

Juvederm Voluma®

This HA-based filler lifts and contours the midface, where cheeks can flatten over time. AboutSkin participated in a clinical trial on Voluma® for the cheeks along with Allergan’s portfolio of other products (the Harmony study, which Dr. Cohen coauthored).


Another hyaluronic acid-based filler, Belotero® serves to fill in moderate to severe nasolabial folds.


Radiesse® is a water-based gel that is filled with calcium-based microspheres that trigger collagen production to restore volume to the face (nasolabial folds) and back of the hands. Dr. Cohen has participated in a cheek clinical trial as well as an ongoing jawline contouring trial using Radiesse®.

What is the Dermal Filler Injection Process?

If you are interested in volume replacement with fillers, please consider scheduling a consultation. Board-Certified Dermatology Physicians will meet personally with you to discuss your aesthetic goals, assess the signs of aging and treatment area, and determine which treatment (or combination of treatments) can work best.

Specific treatment details depend on the filler chosen and how much is used. Time, cost, and the expected scope and duration of results will be discussed at the consultation.

Despite the many variables to take into account, dermal filler sessions all typically work the same way: Needles are used to introduce the chosen filler into the appropriate tissue, which takes a matter of minutes. The treated area will likely feel sensitive and may appear swollen or bruised for a short time after the injections. Obviously, not all folds and lines will resolve, but there should be a noticeable improvement seen in photos—depending on how much volume is used.

Are There More Options for Facial Rejuvenation?

While fillers are ideal for addressing collagen loss, other signs of aging require a different approach. Wrinkles that form due to muscle movement are one example. For this condition, dermatologists use injectables known as neuromodulators, which relax the muscles. Options include BOTOX® Cosmetic, Dysport®, Xeomin®, and Jeuveau. Fillers and neuromodulators can be combined (often leading to a more synergistic effect and even longer duration), as well as incorporated into more global treatment sessions for patients who want to address multiple issues at once.





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What our patients say about us


Dr. Cohen is 'a derm's derm' -- his published research and opinions are sought after by other dermatologists obsessed with the latest innovations in cosmetic dermatology, including lasers, neuromodulators, and fillers. He's also trained many of these derms. Dr. Cohen is arguably one of the best in the U.S., though he's not flashy or self promoting --just intensely focused on achieving elegant, successful results. I stumbled into his practice quite by accident, and could not be happier. His PA Christina is also phenomenal.


I am so pleased with the high level of expertise and care I have received from Dr. Cohen, Dr. Ho and his medical assistants Cristina and Emily. From the Mohs surgery, to a multitude of lasers, to skin checks; the doctors  have been extremely conscientious and strive to have a relationship with their patients.  I am thrilled with the results of my cosmetic procedures and surgery.  In addition, They are kind and very humble providers. It truly is an honor to be a patient of Dr. Cohen and to be a valued patient of his medical practice. Truly the best in the country.. and The World. Thank you Dr. Cohen and Dr. Ho and staff!

Chris J

Have been a patient of Dr. Stoler for a long time. She knows me well and takes excellent care of my skin. Also gives good and appropriate advice!

Judy Saul

Dr. Joel Cohen was highly recommended to me by several other dermatologists for his expertise in laser technology. I was not only impressed with the treatment I received from Dr. Cohen, but also his wonderful, highly skilled staff. The entire experience was top notch!

Linda Aibel

This is the BEST dermatology and cosmetic location you will ever find! Truthfully they give all the attention and care anyone could ask for. I’m always blown away at their kindness and their service. Doctor Jade Fettig always takes her time to talk to me, answer any questions and recommend the best treatment. Highly highly recommend AboutSkinDermatology. You will love it there too guaranteed! =)

Roberta Rachkovsky

Dr. Stoler is the best!

Karen Maxwell

I have been a patient of About Skin Dermatology for over 12 years. Everyone that I have ever encountered at this practice has been knowledgeable and very kind. I see both Dr. Ho and Dr. Cohen. My skin has not looked this good in years. My whole family goes to this practice. I would highly recommend About Skin Dermatology.


Dr Fettig was great- took her time with me and answered my questions. She has a nice bedside manner and good sense of humor.

Cindy Wells

I used Dr. Cohen for a Mohs procedure. He is fellowship trained and extremely competent. Dr. Cohen remained involved in my follow up care with a plastic surgeon and was always readily accessible and available to address my concerns. Both he and the office staff are caring and committed to providing the highest level of professional service. I highly recommend Dr. Cohen. I think it’s very nice.

Richard Z

I have been impressed with my Botox treatment from Dr Cohen at AboutSkin Dermatology. He and his staff are incredibly professional and pleasant. Maddie is always flexible and accommodating with my hectic schedule. Dr. Cohen takes time and a genuine interest in his patients. I highly recommend him for any cosmetic procedures.

Kendra W

Dr Stephen Ho is a fantastic dermatologist. He takes the time to listen to concerns and he patiently and thoroughly explains procedures and diagnostics.

Ben Reeves

Dr. Jade Fettig is so kind, thoughtful, and good at what she does. You can tell she really cares about her patients and makes what could be awkward check-ups into comfortable, and pleasant experiences.The office lounge is clean, updated and really relaxing. Absolutely recommend her as a provider!

Carrie Konczal

Dr Rothstein is amazing. Very thorough during her exams and explains everything as she goes along. The staff is great as well! Best physician I have in the Denver area.

Philip Yost

Dr. Joel Cohen is a superbly skilled dermatologist as well as a most caring doctor who always put his patient's best interest first and foremost

Diana Lee