Dysport® and Xeomin®

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Dysport® and Xeomin®

Get a More Youthful Look by Smoothing Muscle-Related Wrinkles in Denver

Our very own Dr. Joel Cohen literally wrote the textbook on injectables like Dysport® and Xeomin®. The Denver-based Board-Certified Dermatologist at AboutSkin Dermatology and DermSurgery authored 400 pages (the largest to date on this topic) devoted to botulinum toxin-based treatments used most commonly in the field of cosmetic dermatology to relax the facial muscles that cause dynamic wrinkles (wrinkles during animation) to form.

Choosing the right person to inject it makes all the difference. All of the physicians at AboutSkin Dermatology are Board-Certified Dermatologists with experience, training, and know-how in a range of treatments, including Dysport® and Xeomin®, as well as the related BOTOX® Cosmetic and Jeuveau. Aesthetics are not a part time “side-gig” for us—we are well-trained on these procedures, are tested on their nuances in residency and as part of our rigorous board certification, and perform these treatments every day in our offices.

What Do Dysport® and Xeomin® Treat?

Dysport® and Xeomin® are both FDA cleared to reduce the severity of frown lines between the eyebrows. Also known as 11s for the way they resemble the number made of two, short vertical marks, these frown lines are the result of a lifetime of squints and scowls. They can deepen and become more pronounced over time due to some structures and structural support that can be lost through some chronologic aging factors, as well as environmental exposures (like sun exposure, smoke, and other pollutants).

How Do Dysport® and Xeomin® Work?

Muscles contract when they receive a signal to do so via a specialized cell known as a neuron. Dysport® and Xeomin® block contractions in wrinkle-forming muscles by disrupting this typical flow of neuron-signaling.

Once injected into a targeted muscle, the active ingredient in Dysport® and Xeomin®—a purified form of botulinum toxin—interferes with the neurons’ transmission process. The signal chain is disrupted, so muscles stay at rest, even as surrounding muscles respond and pull the skin into specific expressions. This reduced activity can last for months, after which motion gradually returns.

Patients can return for maintenance treatments by routinely scheduling injections or coming in as needed to keep their skin looking smooth.

How Do Dysport® and Xeomin® Differ from Other Neuromodulators?

All neuromodulators work the same way. They have slight variations in terms of how quickly they take effect, how far they can spread from the injection site, how long they last, and other variables.

What Other Wrinkle-Smoothing Treatments Are Available?

While Dysport® and its fellow neuromodulators are ideal for relaxing muscles that cause dynamic wrinkles, other facial lines and creases have different sources and so require different solutions.

Dermal fillers are the treatment of choice for adding volume to areas where collagen loss has led to the formation of static wrinkles, hollows, and other signs of aging. Fillers can work with Dysport® and other injectables to address multiple problems.

In addition to creases, volume loss can also cause skin laxity. Genius® RF and Ultherapy® use energy to promote renewed collagen building for more youthful contours and overall smoother skin.





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What our patients say about us


Dr. Cohen is 'a derm's derm' -- his published research and opinions are sought after by other dermatologists obsessed with the latest innovations in cosmetic dermatology, including lasers, neuromodulators, and fillers. He's also trained many of these derms. Dr. Cohen is arguably one of the best in the U.S., though he's not flashy or self promoting --just intensely focused on achieving elegant, successful results. I stumbled into his practice quite by accident, and could not be happier. His PA Christina is also phenomenal.


I am so pleased with the high level of expertise and care I have received from Dr. Cohen, Dr. Ho and his medical assistants Cristina and Emily. From the Mohs surgery, to a multitude of lasers, to skin checks; the doctors  have been extremely conscientious and strive to have a relationship with their patients.  I am thrilled with the results of my cosmetic procedures and surgery.  In addition, They are kind and very humble providers. It truly is an honor to be a patient of Dr. Cohen and to be a valued patient of his medical practice. Truly the best in the country.. and The World. Thank you Dr. Cohen and Dr. Ho and staff!

Chris J

Have been a patient of Dr. Stoler for a long time. She knows me well and takes excellent care of my skin. Also gives good and appropriate advice!

Judy Saul

Dr. Joel Cohen was highly recommended to me by several other dermatologists for his expertise in laser technology. I was not only impressed with the treatment I received from Dr. Cohen, but also his wonderful, highly skilled staff. The entire experience was top notch!

Linda Aibel

This is the BEST dermatology and cosmetic location you will ever find! Truthfully they give all the attention and care anyone could ask for. I’m always blown away at their kindness and their service. Doctor Jade Fettig always takes her time to talk to me, answer any questions and recommend the best treatment. Highly highly recommend AboutSkinDermatology. You will love it there too guaranteed! =)

Roberta Rachkovsky

Dr. Stoler is the best!

Karen Maxwell

I have been a patient of About Skin Dermatology for over 12 years. Everyone that I have ever encountered at this practice has been knowledgeable and very kind. I see both Dr. Ho and Dr. Cohen. My skin has not looked this good in years. My whole family goes to this practice. I would highly recommend About Skin Dermatology.


Dr Fettig was great- took her time with me and answered my questions. She has a nice bedside manner and good sense of humor.

Cindy Wells

I used Dr. Cohen for a Mohs procedure. He is fellowship trained and extremely competent. Dr. Cohen remained involved in my follow up care with a plastic surgeon and was always readily accessible and available to address my concerns. Both he and the office staff are caring and committed to providing the highest level of professional service. I highly recommend Dr. Cohen. I think it’s very nice.

Richard Z

I have been impressed with my Botox treatment from Dr Cohen at AboutSkin Dermatology. He and his staff are incredibly professional and pleasant. Maddie is always flexible and accommodating with my hectic schedule. Dr. Cohen takes time and a genuine interest in his patients. I highly recommend him for any cosmetic procedures.

Kendra W

Dr Stephen Ho is a fantastic dermatologist. He takes the time to listen to concerns and he patiently and thoroughly explains procedures and diagnostics.

Ben Reeves

Dr. Jade Fettig is so kind, thoughtful, and good at what she does. You can tell she really cares about her patients and makes what could be awkward check-ups into comfortable, and pleasant experiences.The office lounge is clean, updated and really relaxing. Absolutely recommend her as a provider!

Carrie Konczal

Dr Rothstein is amazing. Very thorough during her exams and explains everything as she goes along. The staff is great as well! Best physician I have in the Denver area.

Philip Yost

Dr. Joel Cohen is a superbly skilled dermatologist as well as a most caring doctor who always put his patient's best interest first and foremost

Diana Lee